The CNR2 gene encodes the Cannabinoid Receptor 2 (CB2), a critical class A G-protein-coupled receptor that acts as a vital component of the human endocannabinoid system. Located on human chromosome 1p36.11, this gene regulates how the body manages inflammation, immune responses, and neuroprotection without producing the typical mind-altering effects linked to the nervous system. Core Biological Functions
The CNR2 gene encodes a 360-amino acid protein that shares roughly 44% sequence similarity with its counterpart, the CNR1 (CB1) receptor. While CNR1 primarily governs psychoactive pathways in the central nervous system, CNR2 specializes in protecting tissue and maintaining balance. Gene ResultCNR2 cannabinoid receptor 2 [ (human)] – NCBI
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